Development of Poly Unsaturated Fatty Acid Derivatives of Aspirin for Inhibition of Platelet Function
نویسندگان
چکیده
منابع مشابه
Inhibition of platelet function by cis-unsaturated fatty acids.
The uptake of free fatty acids has previously been shown to affect the capping of lymphocytes, and there is evidence that different types of fatty acids may partition into separate lipid domains in cell surface membranes. In studies of gel-filtered human platelets, we found that cis-unsaturated fatty acids (1-35 microM) inhibited platelet shape change, aggregation, and secretion of 5-hydroxytry...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2016
ISSN: 1521-0103
DOI: 10.1124/jpet.116.234781